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Cobalt-Catalyzed Diastereoselective Reductive [3 + 2] Cycloaddition of Allenes and Enones

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Hong-Tai Chang, Thiruvellore Thatai Jayanth, and Chien-Hong Cheng*

Department of Chemistry, National Tsing Hua University, Hsinchu 30043, Taiwan

J. Am. Chem. Soc., 2007, 129 (14), pp 4166–4167

DOI: 10.1021/ja0710196

Publication Date (Web): March 15, 2007

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, chcheng@mx.nthu.edu.tw

Abstract

Allenes and enones undergo diastereoselective reductive [3 + 2] cycloaddition to form cyclopentanols in very good yields in the presence of CoI₂(dppe), zinc, zinc iodide, and water.

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Published In Issue April 11, 2007
Received February 12, 2007

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Communication

Cobalt-Catalyzed Diastereoselective Reductive [3 + 2] Cycloaddition of Allenes and Enones

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Cobalt-Catalyzed Reductive Coupling of Activated Alkenes with Alkynes

Iridium-Catalyzed Addition of Acid Chlorides to Terminal Alkynes

Total Synthesis of (−)-Acutumine

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