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Asymmetric Conjugate Alkenylation of Enones Catalyzed by Chiral Diols

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T. Robert Wu and J. Michael Chong*

Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry, Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1

J. Am. Chem. Soc., 2007, 129 (16), pp 4908–4909

DOI: 10.1021/ja0713734

Publication Date (Web): April 3, 2007

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, jmchong@uwaterloo.ca

Abstract

Reaction of dimethyl alkenylboronates with α,β-unsaturated ketones in the presence of catalytic amounts of 3,3‘-disubstituted binaphthols provides conjugate alkenylation products in good yields and with generally high (99:1 er) stereoselectivities.

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Published In Issue April 25, 2007
Received February 26, 2007

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Communication

Asymmetric Conjugate Alkenylation of Enones Catalyzed by Chiral Diols

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Ligand-Catalyzed Asymmetric Alkynylboration of Enones: A New Paradigm for Asymmetric Synthesis Using Organoboranes

Asymmetric Petasis Reactions Catalyzed by Chiral Biphenols

Asymmetric Allylboration of Acyl Imines Catalyzed by Chiral Diols

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