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Microwave Activation of Enzymatic Catalysis

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Douglas D. Young^†, Jason Nichols^‡, Robert M. Kelly^‡ and Alexander Deiters ^†

Departments of Chemistry, and Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695

J. Am. Chem. Soc., 2008, 130 (31), pp 10048–10049

DOI: 10.1021/ja802404g

Publication Date (Web): July 10, 2008

, †

Department of Chemistry.

, ‡

Department of Chemical and Biomolecular Engineering.

Section:

Enzymes

Abstract

Microwave irradiation can be used to regulate biocatalysis. Herein, the utilization of hyperthermophilic enzymes in a microwave reactor is reported. While these enzymes are inactive at low temperatures, they can be activated with microwave irradiation. To the best of our knowledge, this is the first illustration of a specific microwave effect in enzymatic catalysis.

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