Research Article
Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 1. Ligand probe groups with the ability to form two hydrogen bonds
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This article has been cited by 37 ACS Journal articles (5 most recent appear below).

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Probing the Dynamic Nature of Water Molecules and Their Influences on Ligand Binding in a Model Binding Site
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Small-Molecule Interferon Inducers. Toward the Comprehension of the Molecular Determinants through Ligand-Based Approaches
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Ira Musmuca, Silvia Simeoni, Antonia Caroli and Rino RagnoJournal of Chemical Information and Modeling2009 49 (7), 1777-1786Hepatitis C is becoming an increasingly common cause of mortality especially in the HIV-coinfected group. Due to the efficacy of interferon (IFN) based therapy in the treatment of hepatitis C, various compounds possessing IFN-inducing activity have been ...

Discovery of Highly Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase by Fragment Hopping
Haitao Ji, Huiying Li, Pavel Martásek, Linda J. Roman, Thomas L. Poulos and Richard B. SilvermanJournal of Medicinal Chemistry2009 52 (3), 779-797Discovery of Highly Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase by Fragment Hopping
Haitao Ji, Huiying Li, Pavel Martásek, Linda J. Roman, Thomas L. Poulos and Richard B. SilvermanJournal of Medicinal Chemistry2009 52 (3), 779-797Selective inhibition of neuronal nitric oxide synthase (nNOS) has been shown to prevent brain injury and is important for the treatment of various neurodegenerative disorders. This study shows that not only greater inhibitory potency and isozyme ...
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- Published In Issue January, 1993
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