Perspective

Tripeptide Motifs in Biology: Targets for Peptidomimetic Design

Phuc Ung and David A. Winkler*
CSIRO Materials Science and Engineering, Bag 10, Clayton South MDC 3169, Australia
Monash Institute of Pharmaceutical Science, Parkville 3152, Australia
J. Med. Chem., 2011, 54 (5), pp 1111–1125
DOI: 10.1021/jm1012984
Publication Date (Web): January 28, 2011
Copyright © 2011 American Chemical Society
*Phone: +61 3 9545 2477. Fax: +61 3 9545 2446. E-mail: dave.winkler@csiro.au.
Biography

Phuc Ung is a Ph.D. candidate at the Monash Institute of Pharmaceutical Sciences (MIPS), Monash University, Melbourne, Australia. He graduated from Monash University in 2007 to obtain his Bachelor’s degree in Medicinal Chemistry. After working extensively to develop new fluorophores using “click chemistry”, he received his Honours degree under the supervision of Dr. Bim Graham. Thereafter, he joined the group of Professor Dave Winkler at CSIRO Molecular and Health Technologies. He is currently working with Dr. Bim Graham and Dr. James D. Swarbrick and is interested in the development of novel lanthanide binding tags and novel application of lanthanides in protein NMR spectroscopy and cellular imaging of GPCRs.

Biography

Dave A. Winkler is a Senior Principal Research Scientist with CSIRO and an Adjunct Professor at Monash University. His research interests have mainly involved molecular design and complex systems. Recently, he has moved into regenerative medicine where he collaborates with international stem cell biologists and tissue engineers. He employs computational methods developed for small molecule research and uses them in these complex biological systems. He was awarded traveling fellowships to Kyoto and Oxford and a Newton Turner Fellowship in 2009. He is a past Board Chairman of the Royal Australian Chemical Institute and past President of Asian Federation for Medicinal Chemistry. He also represents Australia on the committee organizing of Pacifichem. He has published 150 scientific papers and patents.

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Article Views: 3,078 Times
Received 8 October 2010
Published online 28 January 2011
Published in print 10 March 2011
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