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Palladium-Catalyzed Cross-Coupling Reactions of 4-Tosyl-2(5H)-furanone with Boronic Acids: A Facile and Efficient Route to Generate 4-Substituted 2(5H)-Furanones

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Jie Wu,*^† Qiang Zhu,^† Lisha Wang,^† Reza Fathi,^‡ and Zhen Yang*^‡^§

The Aaron Diamond AIDS Research Center, Rockefeller University, 455 First Avenue, New York, New York 10016, VivoQuest, Inc., 711 Executive Blvd., Suite Q, Valley Cottage, New York 10989, and College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China z.yang@vivoquest.com

J. Org. Chem., 2003, 68 (2), pp 670–673

DOI: 10.1021/jo020640f

Publication Date (Web): December 14, 2002

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

†

Rockefeller University.

‡

VivoQuest, Inc.

Peking University.

Abstract

An efficient and facile synthesis of 4-substituted 2(5H)-furanones using palladium catalyzed cross-coupling reactions between 4-tosyl-2(5H)-furanone and boronic acids is reported herein.

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Published In Issue January 24, 2003
Received October 8, 2002

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Palladium-Catalyzed Cross-Coupling Reactions of 4-Tosyl-2(5H)-furanone with Boronic Acids: A Facile and Efficient Route to Generate 4-Substituted 2(5H)-Furanones

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

The First General Palladium Catalyst for the Suzuki−Miyaura and Carbonyl Enolate Coupling of Aryl Arenesulfonates

Enol Tosylates as Viable Partners in Pd-Catalyzed Cross-Coupling Reactions

Versatile Catalysts for the Suzuki Cross-Coupling of Arylboronic Acids with Aryl and Vinyl Halides and Triflates under Mild Conditions

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