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Article

Easy Access to Novel Substituted 6-Aminoimidazo[1,2-a]pyridines Using Palladium- and Copper-Catalyzed Aminations

Supporting Info

Cécile Enguehard,^† Hassan Allouchi,^‡ Alain Gueiffier,*^† and Stephen L. Buchwald^§

EA 3247, Laboratoire de Chimie Thrapeutique, Laboratoire de Chimie Physique, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France, and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

J. Org. Chem., 2003, 68 (11), pp 4367–4370

DOI: 10.1021/jo0341463

Publication Date (Web): April 25, 2003

†

Laboratoire de Chimie Thérapeutique, UFR des Sciences Pharmaceutiques.

‡

Laboratoire de Chimie Physique, UFR des Sciences Pharmaceutiques.

To whom correspondence should be addressed. Fax: + 33 (0)2 47 36 72 88.

Massachusetts Institute of Technology.

, gueiffier@univ-tours.fr

Abstract

Convenient and efficient methods for the preparation of novel 6-aminoimidazo[1,2-a]pyridine derivatives are reported that utilized palladium- or copper-catalyzed methodology. The crystal structure for 6-N-methylanilinoimidazo[1,2-a]pyridine 10 is also described.

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Published In Issue May 30, 2003
Received February 3, 2003

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Article

Easy Access to Novel Substituted 6-Aminoimidazo[1,2-a]pyridines Using Palladium- and Copper-Catalyzed Aminations

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Highly Selective Room-Temperature Copper-Catalyzed C−N Coupling Reactions Highly Selective Room-Temperature Copper-Catalyzed C−N Coupling Reactions

A General and Efficient Copper Catalyst for the Amidation of Aryl Halides

The Copper-Catalyzed N-Arylation of Indoles

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