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RuO₄-Catalyzed Ketohydroxylation of Olefins

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Bernd Plietker*

Organic Chemistry II, Chemistry Faculty, Dortmund University, Otto-Hahn-Str. 6, D-44221 Dortmund, Germany %plietker@pop.uni-dortmund.de

J. Org. Chem., 2003, 68 (18), pp 7123–7125

DOI: 10.1021/jo034864p

Publication Date (Web): August 9, 2003

Corresponding author.

Abstract

A new mild method for the oxidation of a variety of olefins to α-hydroxy ketones is described. Using the concept of a nucleophilic reoxidant, different olefins were ketohydroxylated with high regioselectivity in good to excellent yields.

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Published In Issue September 05, 2003
Received June 20, 2003

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RuO₄-Catalyzed Ketohydroxylation of Olefins