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Magnesium/Methanol: An Effective Reducing Agent for Peroxides

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Peng Dai, Patrick H. Dussault,* and Tony K. Trullinger

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304 pdussault1@unl.edu

J. Org. Chem., 2004, 69 (8), pp 2851–2852

DOI: 10.1021/jo035191d

Publication Date (Web): March 12, 2004

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

Abstract

Magnesium in methanol is an effective reagent for the chemoselective reduction of peroxides, including ozonides. Mg/MeOH is significantly more reactive than Me₂S or PPh₃ and somewhat more reactive than Zn/HOAc.

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Published In Issue April 16, 2004
Received August 14, 2003

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Magnesium/Methanol: An Effective Reducing Agent for Peroxides