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Microwave-Assisted Synthesis of Isonitriles: A General Simple Methodology

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Andrea Porcheddu,* Giampaolo Giacomelli, and Margherita Salaris

Dipartimento di Chimica, Universit degli Studi di Sassari, via Vienna 2, 07100 Sassari anpo@uniss.it

J. Org. Chem., 2005, 70 (6), pp 2361–2363

DOI: 10.1021/jo047924f

Publication Date (Web): February 5, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

Abstract

A facile conversion of formamides to isonitriles under very mild conditions and microwave irradiation is described. This simple and efficient method has been applied for the synthesis of both aliphatic and aromatic isonitriles in high yields.

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Published In Issue March 18, 2005
Received November 23, 2004

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Microwave-Assisted Synthesis of Isonitriles: A General Simple Methodology

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Versatile, Fragrant, Convertible Isonitriles

Ugi-Post Functionalization, from a Single Set of Ugi-Adducts to Two Distinct Heterocycles by Microwave-Assisted Palladium-Catalyzed Cyclizations: Tuning the Reaction Pathways by Ligand Switch

Enantioselective Aza-Darzens Reaction Catalyzed by A Chiral Phosphoric Acid

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