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Synthesis of Isoquinoline Derivatives Using ROM−RCM of Cyclobutene-yne

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Miwako Mori,*^† Hideaki Wakamatsu,^‡ Keisuke Tonogaki,^† Reiko Fujita,^‡ Tsuyoshi Kitamura,^† and Yoshihiro Sato^†

Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, and Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan %mori@pharm.hokudai.ac.jp

J. Org. Chem., 2005, 70 (3), pp 1066–1069

DOI: 10.1021/jo048214c

Publication Date (Web): January 8, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

†

Hokkaido University.

‡

Tohoku Pharmaceutical University.

Abstract

Isoquinoline derivatives were synthesized from cyclobutenylmethylamine derivatives having an alkyne moiety in a tether using a second-generation ruthenium carbene complex under ethylene gas in good yields.

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Published In Issue February 04, 2005
Received October 9, 2004

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Synthesis of Isoquinoline Derivatives Using ROM−RCM of Cyclobutene-yne

Abstract

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History

Recommend & Share

Related Content

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