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Mix-and-Heat Benzylation of Alcohols Using a Bench-Stable Pyridinium Salt
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Abstract

2-Benzyloxy-1-methylpyridinium triflate (1) is a stable, neutral organic salt that converts alcohols into benzyl ethers upon warming. The synthesis and reactivity of 1 are described herein. Benzylation of a wide range of alcohols occurs in good to excellent yield.
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History
- Published In Issue May 12, 2006
- Received February 9, 2006
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