A Sulfitylation−Oxidation Protocol for the Preparation of Sulfates

M. Huibers, Álvaro Manuzi, Floris P. J. T. Rutjes, and Floris L. van Delft*
Institute for Molecules and Materials, Organic Chemistry, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands f.vandelft@science.ru.nl
J. Org. Chem., 2006, 71 (19), pp 7473–7476
DOI: 10.1021/jo060404v
Publication Date (Web): August 16, 2006
Copyright © 2006 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

Abstract

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A novel, high-yielding method for sulfation of alcohols has been developed, proceeding via sulfite- and sulfate diester intermediates. Sulfite diesters serve as versatile sulfate monoester precursors, allowing for transformations that are difficult or impossible with the latter compounds.

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History

  • Published In Issue September 15, 2006
  • Received February 26, 2006

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