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Article

Synthesis of 1,3,5-Tricarbonyl Derivatives by Condensation of 1,3-Bis(silyl enol ethers) with Acid Chlorides

Supporting Info

Thomas Rahn,^†^‡ Van T. H. Nguyen,^† T. H. Tam Dang,^†^‡ Zafar Ahmed,^†^‡ Karen Methling,^§ Michael Lalk,^§ Christine Fischer,^‡ Anke Spannenberg,^‡ and Peter Langer*^†^‡

Institut fr Chemie, Universitt Rostock, Albert-Einstein-Strasse 3a, 18059 Rostock, Germany, Leibniz-Institut fr Katalyse e. V. an der Universitt Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany, and Institut fr Pharmazie, Universitt Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17487 Greifswald, Germany

J. Org. Chem., 2007, 72 (6), pp 1957–1961

DOI: 10.1021/jo062153w

Publication Date (Web): February 8, 2007

†

Institut für Chemie, Universität Rostock.

‡

Leibniz-Institut für Katalyse e. V. an der Universität Rostock.

Institut für Pharmazie, Universität Greifswald.

To whom correspondence should be addressed. Fax: +381 4986412.

, peter.langer@uni-rostock.de

Abstract

A variety of 1,3,5-tricarbonyl derivatives were prepared by reaction of 1,3-bis(silyl enol ethers) with acid chlorides under mild conditions. This includes reactions of both aromatic and aliphatic acid chlorides and bis(acid chlorides). The yields vary depending on the type of acid chloride employed.

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Published In Issue March 16, 2007
Received October 17, 2006

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Article

Synthesis of 1,3,5-Tricarbonyl Derivatives by Condensation of 1,3-Bis(silyl enol ethers) with Acid Chlorides

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Efficient Synthesis of Salicylates by Catalytic [3 + 3] Cyclizations of 1,3-Bis(silyl enol ethers) with 1,1,3,3-Tetramethoxypropane

Nitrile Biotransformations for the Efficient Synthesis of Highly Enantiopure 1-Arylaziridine-2-carboxylic Acid Derivatives and Their Stereoselective Ring-Opening Reactions

Synthesis of Dibenzo[b,d]pyran-6-ones Based on [3 + 3] Cyclizations of 1,3-Bis(silyl enol ethers) with 3-Silyloxy-2-en-1-ones

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