Rhodium-Catalyzed Intramolecular C−H Insertion of α-Aryl-α-diazo Ketones

Douglass F. Taber* and Weiwei Tian
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716
J. Org. Chem., 2007, 72 (9), pp 3207–3210
DOI: 10.1021/jo0624694
Publication Date (Web): March 27, 2007
Copyright © 2007 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, taberdf@udel.edu

Abstract

Abstract Image

Direct diazo transfer proceeds smoothly with α-aryl ketones. The derived α-aryl-α-diazo ketones cyclize efficiently with Rh catalysis to give the corresponding α-aryl cyclopentanones.

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History

  • Published In Issue April 27, 2007
  • Received December 2, 2006

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