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An Improved Procedure for the Three-Component Synthesis of Highly Substituted Pyridines Using Ionic Liquid
In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.
Abstract

A basic ionic liquid, [bmIm]OH, efficiently promotes a one-pot, three-component condensation of aldehydes, malononitrile, and thiophenols to produce highly substituted pyridines in high yields at room temperature. This reaction does not involve any hazardous organic solvent and toxic catalyst. The ionic liquid is recovered and recycled for subsequent reactions.
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History
- Published In Issue April 13, 2007
- Received January 4, 2007
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