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An N-Aryl-Substituted Oxazolidinone-Containing Ketone-Catalyzed Asymmetric Epoxidation with Hydrogen Peroxide as the Primary Oxidant

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Christopher P. Burke, Lianhe Shu, and Yian Shi*

Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523 yian@lamar.colostate.edu

J. Org. Chem., 2007, 72 (16), pp 6320–6323

DOI: 10.1021/jo0708644

Publication Date (Web): July 10, 2007

Address correspondence to this author. Phone: 970-491-7424. Fax: 970-491-1801.

Abstract

Asymmetric epoxidation of various olefins with an N-aryl-substituted oxazolidinone-containing ketone as catalyst and hydrogen peroxide as the primary oxidant has been investigated, and up to 96% ee was obtained.

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Published In Issue August 03, 2007
Received April 26, 2007

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Note

An N-Aryl-Substituted Oxazolidinone-Containing Ketone-Catalyzed Asymmetric Epoxidation with Hydrogen Peroxide as the Primary Oxidant

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Practical Synthesis of an l-Fructose-Derived Ketone Catalyst for Asymmetric Epoxidation of Olefins

Effective Asymmetric Epoxidation of Styrenes by Chiral Dioxirane

Enantioselective Synthesis of γ-Aryl-γ-butyrolactones by Sequential Asymmetric Epoxidation, Ring Expansion, and Baeyer−Villiger Oxidation

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