Oppenauer Oxidation of Secondary Alcohols with 1,1,1-Trifluoroacetone as Hydride Acceptor

Rossella Mello, Jaime Martínez-Ferrer, Gregorio Asensio,* and María Elena González-Núñez
Departamento de Química Orgánica, Universidad de Valencia, Avda. V. Andrés Estellés s/n, 46100-Burjassot (Valencia), Spain gregorio.asensio@uv.es
J. Org. Chem., 2007, 72 (24), pp 9376–9378
DOI: 10.1021/jo7016422
Publication Date (Web): November 2, 2007
Copyright © 2007 American Chemical Society

Abstract

Abstract Image

1,1,1-Trifluoroacetone (2a) reacts as a hydride-acceptor in the Oppenauer oxidation of secondary alcohols (1) in the presence of diethylethoxyaluminum. The oxidant allows for selective oxidation of secondary alcohols in the presence of primary alcohols.

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This article has been cited by 1 ACS Journal articles (1 most recent appear below).

  • Cover Image

    How Trifluoroacetone Interacts with Water

    Laura B. Favero, Luca Evangelisti, Assimo Maris, Alicia Vega-Toribio, Alberto Lesarri, and Walther Caminati
    The Journal of Physical Chemistry A2011 115 (34), 9493-9497
    • How Trifluoroacetone Interacts with Water

      Laura B. Favero, Luca Evangelisti, Assimo Maris, Alicia Vega-Toribio, Alberto Lesarri, and Walther Caminati
      The Journal of Physical Chemistry A2011 115 (34), 9493-9497

      The rotational spectra of five isotopologues of the molecular adduct 1,1,1-trifluoroacetone−water have been assigned using pulsed-jet Fourier-transform microwave spectroscopy. All rotational transitions appear as doublets, due to the internal rotation of ...

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History

  • Published In Issue November 23, 2007
  • Received July 26, 2007

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