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Novel One-Pot, Three-Component Synthesis of New 2-Alkyl-5-aryl-(1H)-pyrrole-4-ol in Water
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Abstract
New 2-alkyl-5-aryl-(1H)-pyrrole-4-ol derivatives were synthesized via three-component reaction of β-dicarbonyl compounds with arylglyoxals in the presence of ammonium acetate in water at room temperature.
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This article has been cited by 7 ACS Journal articles (5 most recent appear below).
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Heng-Yen Wang, Daniel S. Mueller, Rachna M. Sachwani, Rachel Kapadia, Hannah N. Londino, and Laura L. AndersonThe Journal of Organic Chemistry2011 76 (9), 3203-3221The regioselective synthesis of 2,3,4- or 2,3,5-trisubstituted pyrroles has been achieved via [3,3] and [1,3] sigmatropic rearrangements of O-vinyl oximes, respectively. Iridium-catalyzed isomerization of easily prepared O-allyl oximes enables rapid ...
Carbon−Carbon Bond Formation and Pyrrole Synthesis via the [3,3] Sigmatropic Rearrangement of O-Vinyl Oxime Ethers
Heng-Yen Wang, Daniel S. Mueller, Rachna M. Sachwani, Hannah N. Londino and Laura L. AndersonOrganic Letters2010 12 (10), 2290-2293Carbon−Carbon Bond Formation and Pyrrole Synthesis via the [3,3] Sigmatropic Rearrangement of O-Vinyl Oxime Ethers
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Iron(III)-Catalyzed Four-Component Coupling Reaction of 1,3-Dicarbonyl Compounds, Amines, Aldehydes, and Nitroalkanes: A Simple and Direct Synthesis of Functionalized Pyrroles
Sukhendu Maiti, Srijit Biswas and Umasish JanaThe Journal of Organic Chemistry2010 75 (5), 1674-1683Iron(III)-Catalyzed Four-Component Coupling Reaction of 1,3-Dicarbonyl Compounds, Amines, Aldehydes, and Nitroalkanes: A Simple and Direct Synthesis of Functionalized Pyrroles
Sukhendu Maiti, Srijit Biswas and Umasish JanaThe Journal of Organic Chemistry2010 75 (5), 1674-1683A simple, convenient, and multicomponent coupling strategy for the synthesis of highly functionalized pyrroles catalyzed by iron(III) salts has been developed. This strategy demonstrated four-component coupling reactions of 1,3-dicarbonyl compounds, ...
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More Sustainable Approaches for the Synthesis of N-Based Heterocycles
Nuno R. Candeias, Luís C. Branco, Pedro M. P.Gois, Carlos A. M. Afonso and Alexandre F. TrindadeChemical Reviews2009 109 (6), 2703-2802More Sustainable Approaches for the Synthesis of N-Based Heterocycles
Nuno R. Candeias, Luís C. Branco, Pedro M. P.Gois, Carlos A. M. Afonso and Alexandre F. TrindadeChemical Reviews2009 109 (6), 2703-2802
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History
- Published In Issue March 21, 2008
- Received November 4, 2007
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