An Easy Microwave-Assisted Synthesis of Sulfonamides Directly from Sulfonic Acids

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Abstract

An easy and handy synthesis of sulfonamides directly from sulfonic acids or its sodium salts is reported. The reaction is performed under microwave irradiation, has shown a good functional group tolerance, and is high yielding.

Citing Articles

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This article has been cited by 2 ACS Journal articles (2 most recent appear below).

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  Synthesis and Cross-Coupling of Sulfonamidomethyltrifluoroborates

  Gary A. Molander, Nicolas Fleury-Brégeot, and Marie-Aude Hiebel
  Organic Letters2011 13 (7), 1694-1697

  • Synthesis and Cross-Coupling of Sulfonamidomethyltrifluoroborates

    Gary A. Molander, Nicolas Fleury-Brégeot, and Marie-Aude Hiebel
    Organic Letters2011 13 (7), 1694-1697

    Sulfonamidomethyltrifluoroborates were successfully synthesized and cross-coupled with a wide range of aryl and heteroaryl chlorides, allowing the construction of a sulfonamidomethyl aryl linkage through a new disconnection, thus offering a new way to ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Dynamic ¹H NMR Spectroscopic Study of the Ring Inversion in N-Sulfonyl Morpholines—Studies on N−S Interactions

  Ali Reza Modarresi-Alam, Homeyra Alsadat Amirazizi, Hajar Bagheri, Hamid-Reza Bijanzadeh and Erich Kleinpeter
  The Journal of Organic Chemistry2009 74 (13), 4740-4746

  • Dynamic ¹H NMR Spectroscopic Study of the Ring Inversion in N-Sulfonyl Morpholines—Studies on N−S Interactions

    Ali Reza Modarresi-Alam, Homeyra Alsadat Amirazizi, Hajar Bagheri, Hamid-Reza Bijanzadeh and Erich Kleinpeter
    The Journal of Organic Chemistry2009 74 (13), 4740-4746

    The effect of the exocyclic conjugation, via d−p orbital interaction and/or negative hyperconjugation (anomeric effect) of the N−S bond, on the inversion of the morpholine ring in some N-arylsulfonyl morpholines is studied by variable-temperature 1H NMR ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links

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