Gold Nanoparticles Prepared Using Cape Aloe Active Components

Željka Krpetić, Giorgio Scarì, Enrico Caneva, Giovanna Speranza and Francesca Porta*
Dipartimento di Chimica Inorganica Metallorganica Analitica “Lamberto Malatesta”, University of Milan, Via Venezian 21, Milan, Italy
Dipartimento di Biologia 7B, University of Milan, Via Celoria 26, Milan, Italy
§ Centro Interdipartimentale Grandi Apparecchiature-CIGA
Dipartimento di Chimica Organica e Industriale
University of Milan, Via Golgi 19, Milan, Italy
Langmuir, 2009, 25 (13), pp 7217–7221
DOI: 10.1021/la9009674
Publication Date (Web): June 8, 2009
Copyright © 2009 American Chemical Society
*To whom correspondence should be addressed. Telephone: +390250314361. Fax: +390250314405. E-mail: Francesca.Porta@unimi.it.

Abstract

Abstract Image

A novel use of two components of Cape aloe, aloin A and aloesin, acting as stabilizers in the preparation of gold and silver nanoparticles, is reported. Stable water-soluble particles of different size and shape are prepared by varying the reaction conditions, temperature, reaction time, and reducing agents. Characterization of the obtained particles is performed using UV−visible, attenuated total reflection Fourier transform infrared (ATR-FTIR), and 1H NMR spectroscopies and transmission electron microscopy (TEM). The efficient cellular uptake of 50 nm sized aloin A and aloesin stabilized gold particles into macrophages and HeLa cells was investigated, proposing these particles as nanovehicles.

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History

  • Published In Issue July 07, 2009
  • Article ASAPJune 08, 2009
  • Received: March 19, 2009
    Revised: May 05, 2009

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