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Abstract

Incorporation of CdSe/ZnS semiconductor quantum dots (QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly(ethylene glycol) (PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation.

Citing Articles

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This article has been cited by 16 ACS Journal articles (5 most recent appear below).

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  Using Polymer Conformation to Control Architecture in Semiconducting Polymer/Viral Capsid Assemblies

  Benny C. Ng, Stephanie T. Chan, Jason Lin, and Sarah H. Tolbert
  ACS Nano2011 5 (10), 7730-7738

  • Using Polymer Conformation to Control Architecture in Semiconducting Polymer/Viral Capsid Assemblies

    Benny C. Ng, Stephanie T. Chan, Jason Lin, and Sarah H. Tolbert
    ACS Nano2011 5 (10), 7730-7738

    Cowpea chlorotic mottle virus is a single-stranded RNA plant virus with a diameter of 28 nm. The proteins comprising the capsid of this virus can be purified and reassembled either by themselves to form hollow structures or with polyanions such as double-...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Photothermal Imaging and Measurement of Protein Shell Stoichiometry of Single HIV-1 Gag Virus-like Nanoparticles

  Mario Vieweger, Nancy Goicochea, Eun Sohl Koh, and Bogdan Dragnea
  ACS Nano2011 5 (9), 7324-7333

  • Photothermal Imaging and Measurement of Protein Shell Stoichiometry of Single HIV-1 Gag Virus-like Nanoparticles

    Mario Vieweger, Nancy Goicochea, Eun Sohl Koh, and Bogdan Dragnea
    ACS Nano2011 5 (9), 7324-7333

    Virus life stages often constitute a complex chain of events, difficult to track in vivo and in real-time. Challenges are associated with spatial and time limitations of current probes: most viruses are smaller than the diffraction limit of optical ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus–Quantum Dot Conjugates

  Kye-Il Joo, Yun Fang, Yarong Liu, Liang Xiao, Zhen Gu, April Tai, Chi-Lin Lee, Yi Tang, and Pin Wang
  ACS Nano2011 Article ASAP

  • Enhanced Real-Time Monitoring of Adeno-Associated Virus Trafficking by Virus–Quantum Dot Conjugates

    Kye-Il Joo, Yun Fang, Yarong Liu, Liang Xiao, Zhen Gu, April Tai, Chi-Lin Lee, Yi Tang, and Pin Wang
    ACS Nano2011 Article ASAP

    The unique spectral properties of semiconductor quantum dots (QDs) enable long-term live-cell imaging and ultrasensitive detection of viral particles, which in turn can potentially provide a practical means for detailed analysis of the underlying ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Magnetic Nanoparticles-Templated Assembly of Protein Subunits: A New Platform for Carbohydrate-Based MRI Nanoprobes

  Elsa Valero, Stefano Tambalo, Pasquina Marzola, Mariano Ortega-Muñoz, F. Javier López-Jaramillo, Francisco Santoyo-González, Juan de Dios López, Juan J. Delgado, José J. Calvino, Rafael Cuesta, José M. Domínguez-Vera, and Natividad Gálvez
  Journal of the American Chemical Society2011 133 (13), 4889-4895

  • Magnetic Nanoparticles-Templated Assembly of Protein Subunits: A New Platform for Carbohydrate-Based MRI Nanoprobes

    Elsa Valero, Stefano Tambalo, Pasquina Marzola, Mariano Ortega-Muñoz, F. Javier López-Jaramillo, Francisco Santoyo-González, Juan de Dios López, Juan J. Delgado, José J. Calvino, Rafael Cuesta, José M. Domínguez-Vera, and Natividad Gálvez
    Journal of the American Chemical Society2011 133 (13), 4889-4895

    A new approach for the preparation of carbohydrate-coated magnetic nanoparticles is reported. In a first step, we show that the pH-driven assembly-disassembly natural process that occurs in apoferritin protein is effective for the encapsulation of ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links
• 

  Magnetic Virus-like Nanoparticles in N. benthamiana Plants: A New Paradigm for Environmental and Agronomic Biotechnological Research

  Xinlei Huang, Barry D. Stein, Hu Cheng, Andrey Malyutin, Irina B. Tsvetkova, David V. Baxter, Nicholas B. Remmes, Jeanmarie Verchot, Cheng Kao, Lyudmila M. Bronstein, and Bogdan Dragnea
  ACS Nano2011 Article ASAP

  • Magnetic Virus-like Nanoparticles in N. benthamiana Plants: A New Paradigm for Environmental and Agronomic Biotechnological Research

    Xinlei Huang, Barry D. Stein, Hu Cheng, Andrey Malyutin, Irina B. Tsvetkova, David V. Baxter, Nicholas B. Remmes, Jeanmarie Verchot, Cheng Kao, Lyudmila M. Bronstein, and Bogdan Dragnea
    ACS Nano2011 Article ASAP

    This article demonstrates the encapsulation of cubic iron oxide nanoparticles (NPs) by Brome mosaic virus capsid shells and the formation, for the first time, of virus-based nanoparticles (VNPs) with cubic cores. Cubic iron oxide NPs functionalized with ...

    Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links

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