Detecting Simulated Patterns of Lung Cancer Biomarkers by Random Network of Single-Walled Carbon Nanotubes Coated with Nonpolymeric Organic Materials

Gang Peng, Elena Trock and Hossam Haick*
The Department of Chemical Engineering and Russell Barrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa 32000, Israel
Nano Lett., 2008, 8 (11), pp 3631–3635
DOI: 10.1021/nl801577u
Publication Date (Web): October 8, 2008
Copyright © 2008 American Chemical Society
* To whom correspondence should be addressed. E-mail: hhossam@technion.ac.il.

Abstract

Abstract Image

An array of chemiresistive random network of single-walled carbon nanotubes coated with nonpolymeric organic materials shows a high potential for diagnosis of lung cancer via breath samples. The sensors array shows excellent discrimination between the volatile organic compounds (VOCs) found in the breath of patients with lung cancer, relative to healthy controls, especially if the sensors array is preceded with either water extractor and/or preconcentrator of VOCs. The pattern compositions of the healthy and cancerous states were determined by gas-chromatography linked with mass-spectroscopy (GC-MS) analysis of real exhaled breath.

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History

  • Published In Issue November 12, 2008
  • Article ASAPOctober 08, 2008
  • Received: June 03, 2008
    Revised: August 03, 2008

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