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Greener Nanoscience: A Proactive Approach to Advancing Applications and Reducing Implications of Nanotechnology
As nanotechnology emerges from the discovery phase, the real and/or perceived negative impacts need to be addressed lest they become barriers to future development of the field.
Without relevant data, innovators are forced to rely on “reasonable worst case scenarios” in applying risk management frameworks or they may not discover product hazards until late in product development.
Interdisciplinary teams that partner life, environmental, and nanomaterials scientists need to work together to define standard approaches and share expertise to accelerate the collection of definitive data on nanomaterial hazards given their complexity.
Green nanoscience, like green chemistry, strives to reduce or eliminate hazards to human health and the environment through product design and process optimization.
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Abstract
Nanotechnology continues to offer new materials and applications that will benefit society, yet there is growing concern about the potential health and environmental impacts of production and use of nanoscale products. Although hundreds of studies of nanomaterial hazards have been reported, due (largely) to the complexity of the nanomaterials, there is no consensus about the impact these hazards will have. This Focus describes the need for a research agenda that addresses these nanomaterial complexities through coordinated research on the applications and implications of new materials, wherein nanomaterials scientists play a central role as we move from understanding to minimizing nanomaterial hazards. Greener nanoscience is presented as an approach to determining and implementing the design rules for safer nanomaterials and safer, more efficient processes.
Citing Articles
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This article has been cited by 14 ACS Journal articles (5 most recent appear below).
Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays
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Stacey L. Harper, Jason Lee Carriere, John M. Miller, James Evan Hutchison, Bettye L. S. Maddux, and Robert L. TanguayACS Nano2011 Article ASAPThe challenge of optimizing both performance and safety in nanomaterials hinges on our ability to resolve which structural features lead to desired properties. It has been difficult to draw meaningful conclusions about biological impacts from many studies ...
Single-Step Biofriendly Synthesis of Surface Modifiable, Near-Spherical Gold Nanoparticles for Applications in Biological Detection and Catalysis
Vivek D. Badwaik, Jane J. Bartonojo, Jesse W. Evans, Shivendra V. Sahi, Chad B. Willis, and Rajalingam DakshinamurthyLangmuir2011 27 (9), 5549-5554Single-Step Biofriendly Synthesis of Surface Modifiable, Near-Spherical Gold Nanoparticles for Applications in Biological Detection and Catalysis
Vivek D. Badwaik, Jane J. Bartonojo, Jesse W. Evans, Shivendra V. Sahi, Chad B. Willis, and Rajalingam DakshinamurthyLangmuir2011 27 (9), 5549-5554There is an increased interest in understanding the toxicity and rational design of gold nanoparticles (GNPs) for biomedical applications in recent years. Such efforts warrant reliable, viable, and biofriendly synthetic methodology for GNPs with ...
Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos
Tian Xia, Yan Zhao, Tina Sager, Saji George, Suman Pokhrel, Ning Li, David Schoenfeld, Huan Meng, Sijie Lin, Xiang Wang, Meiying Wang, Zhaoxia Ji, Jeffrey I. Zink, Lutz Mädler, Vincent Castranova, Shuo Lin, and Andre E. NelACS Nano2011 5 (2), 1223-1235Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos
Tian Xia, Yan Zhao, Tina Sager, Saji George, Suman Pokhrel, Ning Li, David Schoenfeld, Huan Meng, Sijie Lin, Xiang Wang, Meiying Wang, Zhaoxia Ji, Jeffrey I. Zink, Lutz Mädler, Vincent Castranova, Shuo Lin, and Andre E. NelACS Nano2011 5 (2), 1223-1235We have recently shown that the dissolution of ZnO nanoparticles and Zn2+ shedding leads to a series of sublethal and lethal toxicological responses at the cellular level that can be alleviated by iron doping. Iron doping changes the particle matrix and ...
Uncovering the Design Rules for Peptide Synthesis of Metal Nanoparticles
Yen Nee Tan, Jim Yang Lee and Daniel I. C. WangJournal of the American Chemical Society2010 132 (16), 5677-5686Uncovering the Design Rules for Peptide Synthesis of Metal Nanoparticles
Yen Nee Tan, Jim Yang Lee and Daniel I. C. WangJournal of the American Chemical Society2010 132 (16), 5677-5686Peptides are multifunctional reagents (reducing and capping agents) that can be used for the synthesis of biocompatible metal nanoparticles under relatively mild conditions. However, the progress in peptide synthesis of metal nanoparticles has been slow ...
Sustainability through Nanotechnology
Paul S. WeissEditor-in-Chief and Penelope A. LewisManaging EditorACS Nano2010 4 (3), 1249-1250Sustainability through Nanotechnology
Paul S. WeissEditor-in-Chief and Penelope A. LewisManaging EditorACS Nano2010 4 (3), 1249-1250
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- Published In Issue March 25, 2008
- Article ASAPMarch 25, 2008
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