Suberosols A−D, Four New Sesquiterpenes with β-Caryophyllene Skeletons from a Taiwanese Gorgonian Coral Subergorgia suberosa

Guey-Horng Wang,† Atallah F. Ahmed,†‡ Jyh-Horng Sheu,*† Chang-Yih Duh,† Ya-Ching Shen,† and Li-Tang Wang†
Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, Republic of China, and Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
J. Nat. Prod., 2002, 65 (6), pp 887–891
DOI: 10.1021/np010586i
Publication Date (Web): June 1, 2002
Copyright © 2002 American Chemical Society and American Society of Pharmacognosy
†

 National Sun-Yat-Sen University.

,
‡

 Mansoura University.

,
*

 To whom correspondence should be addressed. Tel:  886-7-5252000, ext. 5030. Fax:  886-7-5255020. E-mail:  sheu@mail.nsysu.edu.tw.

Abstract

Four new β-caryophyllene-derived sesquiterpenes alcohols, suberosols A (1), B (2), C (3), and D (4), along with two known β-caryophyllene-derived sesqueterpene ketones, buddledins C (5) and D (6), were isolated from a Taiwanese gorgonian coral Subergorgia suberosa. The structures of 1−4 were determined on the basis of extensive spectroscopic analyses. Cytotoxicity of these compounds toward various cancer cell lines is also described.

View: Full Text HTML | Hi-Res PDF

Tools

History

  • Published In Issue June 28, 2002
  • Received November 21, 2001

Recommend & Share

Related Content

Other ACS content by these authors: