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Article

Pachyclavulariolides M−R, Six Novel Diterpenoids from a Taiwanese Soft Coral Pachyclavularia violacea

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Jyh-Horng Sheu,*^† Guey-Horng Wang,^†^‡ Chang-Yih Duh,^† and Keryea Soong^§

Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, Center for General Education, Hsing-Kuo University, Tainan 709, Taiwan, and Institute of Marine Biology, National Sun Yat-Sen University, Kaohsiung 804, Taiwan

J. Nat. Prod., 2003, 66 (5), pp 662–666

DOI: 10.1021/np020603j

Publication Date (Web): May 8, 2003

To whom correspondence should be addressed. Tel: 886-7-5252000, ext. 5030. Fax: 886-7-5255020. E-mail: sheu@mail.nsysu.edu.tw.

†

Department of Marine Resources, National Sun Yat-Sen University.

‡

Hsing-Kuo University.

Institute of Marine Biology, National Sun Yat-Sen University.

Abstract

Six novel diterpenoids, pachyclavulariolides M−R (1−6), have been isolated from a Taiwanese soft coral Pachyclavularia violacea. The structures and relative stereochemistry of compounds 1−6 were established by spectroscopic analyses. Compound 1 has been shown to exhibit significant cytotoxicity toward P-388 cancer cells. Biosynthesis of 4−6 is discussed.

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Published In Issue May 23, 2003
Received December 31, 2002

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Article

Pachyclavulariolides M−R, Six Novel Diterpenoids from a Taiwanese Soft Coral Pachyclavularia violacea

Abstract

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History

Recommend & Share

Related Content

Pachyclavulariaenones D−G, New Diterpenoids from the Soft Coral Pachyclavularia violacea

Suberosols A−D, Four New Sesquiterpenes with β-Caryophyllene Skeletons from a Taiwanese Gorgonian Coral Subergorgia suberosa

Junceol A, a New Sesquiterpenoid from the Sea Pen Virgularia juncea

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