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Majusculoic Acid, a Brominated Cyclopropyl Fatty Acid from a Marine Cyanobacterial Mat Assemblage

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John B. MacMillan and Tadeusz F. Molinski*

Department of Chemistry, University of California, Davis, California 95616

J. Nat. Prod., 2005, 68 (4), pp 604–606

DOI: 10.1021/np049596k

Publication Date (Web): March 26, 2005

To whom correspondence should be addressed. Tel: +01 530 752-6358. Fax: +01 530 752-6358. E-mail: tfmolinski@ucdavis.edu.

Abstract

The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 μM).

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Published In Issue April 22, 2005
Received December 13, 2004

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Note

Majusculoic Acid, a Brominated Cyclopropyl Fatty Acid from a Marine Cyanobacterial Mat Assemblage

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Isolation and Structure of the Cytotoxin Lyngbyabellin B and Absolute Configuration of Lyngbyapeptin A from the Marine Cyanobacterium Lyngbya majuscula

Two New Chymotrypsin Inhibitors Isolated from the Cyanobacterium Microcystis aeruginosa NIES-88

Pitipeptolides A and B, New Cyclodepsipeptides from the Marine Cyanobacterium Lyngbya majuscula

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