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Tigliane Diterpenoids from the Stem Bark of Neoboutonia macrocalyx

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Peter G. Kirira,^†^‡ Geoffrey M. Rukunga,^‡ Alphonse W. Wanyonyi,^† Charles N. Muthaura,^‡ Geoffrey M. Mungai,^§ Alex K. Machocho,^† and Isaiah O. Ndiege*^†

Department of Chemistry, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844, Nairobi 00100, Kenya, Center for Traditional Medicine and Drug Research, Kenya Medical Research Institute, P.O. Box 54840, Nairobi 00200, Kenya, and East Africa Herbarium, National Museums of Kenya, P.O. Box 40658, Nairobi 00100, Kenya

J. Nat. Prod., 2007, 70 (5), pp 842–845

DOI: 10.1021/np0604174

Publication Date (Web): March 24, 2007

†

Kenyatta University.

‡

Kenya Medical Research Institute.

East Africa Herbarium.

Corresponding author. Tel: +254-20-810901, +254-20-811622. Fax: +254-20-811575. E-mail: indiege@icipe.org.

Abstract

Neoboutonia macrocalyx is a plant used by traditional healers among the Meru community in Kenya. Chromatographic fractionation of the petroleum ether and dichloromethane extracts of this plant yielded one known (1) and three new tigliane-type diterpenoids (2−4). The chemical structures of the isolated compounds were established through spectroscopic data interpretation.

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Published In Issue May 25, 2007
Received August 23, 2006

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Tigliane Diterpenoids from the Stem Bark of Neoboutonia macrocalyx

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Crotonkinins A and B and Related Diterpenoids from Croton tonkinensis as Anti-inflammatory and Antitumor Agents

Unsaturated Diterpenoids with a Novel Carbocyclic Skeleton from Salvia xalapensis

Natural Product Extracts of Plant and Marine Origin Having Antileukemia Potential. The NCI Experience

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