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Neo-clerodane Diterpenes from the Hallucinogenic Sage Salvia divinorum

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Laboratory of Pharmacognosy and Natural Product Chemistry, Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, 1314-1 Shido, Sanuki-City, Kagawa 769-2193, Japan
Cite this: J. Nat. Prod. 2006, 69, 12, 1782–1786
Publication Date (Web):November 17, 2006
https://doi.org/10.1021/np060456f
Copyright © 2006 American Chemical Society and American Society of Pharmacognosy
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    Abstract

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    Seven new neo-clerodane diterpenes, salvidivins A (2), B, (3), C (4), and D (5), salvinorins H (6) and I (7), and divinorin F (8), along with eight known neo-clerodane diterpenes, salvinorins A (1)−F, divinatorins A and B, and seven other constituents, were isolated from the hallucinogenic sage Salvia divinorum. The structures of 1−7 were elucidated on the basis of 2D NMR spectroscopic studies.

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