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Article

Antiprotozoal Polyacetylenes from the Tanzanian Medicinal Plant Cussonia zimmermannii

Martin Senn^†, Sigmund Gunzenhauser^†, Reto Brun^‡ and Urs Séquin*^†

Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel, Switzerland, and Swiss Tropical Institute, Socinstrase 57, CH-4051 Basel, Switzerland

J. Nat. Prod., 2007, 70 (10), pp 1565–1569

DOI: 10.1021/np0702133

Publication Date (Web): October 9, 2007

†

University of Basel.

‡

Swiss Tropical Institute.

* To whom correspondence should be addressed. Tel: +41 61 267 11 10. Fax: +41 61 267 11 03. E-mail: urs.sequin@unibas.ch.

Abstract

From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1–4, were isolated, three of which (1–3) were active against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Plasmodium falciparum, and Leishmania donovani.

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Published In Issue October 26, 2007
Article ASAPOctober 09, 2007
Received: May 07, 2007

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Article

Antiprotozoal Polyacetylenes from the Tanzanian Medicinal Plant Cussonia zimmermannii

Abstract

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Recommend & Share

Related Content

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Trypanocidal and Antileishmanial Dihydrochelerythrine Derivatives from Garcinia lucida

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