Prev. Article Next Article Table of Contents

Article

Rhabdastrellins A−F, Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella aff. distincta

Figures
Citing Articles

Your current credentials do not allow retrieval of the full text.

Purchase the full-text

PDF/HTML,
figures/images,
references and tables,
(where available)

Fang Lv^†, Minjuan Xu^†, Zhiwei Deng^‡, Nicole J. de Voogd^§, Rob W. M. van Soest^§, Peter Proksch and Wenhan Lin*^†

State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, People's Republic of China, Analytical and Testing Center, Beijing Normal University, Beijing, 100875, People's Republic of China, National Museum of Natural History Naturalis, 2300 RA Leiden, The Netherlands, Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine University, 40225 Duesseldorf, Germany, and College of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, People's Republic of China

J. Nat. Prod., 2008, 71 (10), pp 1738–1741

DOI: 10.1021/np800324v

Publication Date (Web): October 1, 2008

* To whom correspondence should be addressed. Tel: +86 10 82806188. E-mail: whlin@bjmu.edu.cn., †

Peking University.

, ‡

Beijing Normal University.

, §

National Museum of Natural History Naturalis.

Heinrich-Heine University.

Beijing Institute of Technology.

Section:

Nonmammalian Biochemistry

Abstract

Chemical examination of the marine sponge Rhabdastrella aff. distincta resulted in the isolation of six new isomalabaricane triterpenes, rhabdastrellins A−F (1−6), which were present as minor components, along with stellettins L and M. Their structures were elucidated on the basis of extensive spectroscopic data analyses and comparison with spectroscopic data of known analogues. The cytotoxicity of compounds 1−6 against a small panel of human tumor cell lines was also evaluated.

View: Full Text HTML | Hi-Res PDF | PDF w/ Links

Citing Articles

View all 1 citing articles

Citation data is made available by participants in CrossRef's Cited-by Linking service. For a more comprehensive list of citations to this article, users are encouraged to perform a search in SciFinder.

This article has been cited by 1 ACS Journal articles (1 most recent appear below).

Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata
Miyabi Hirashima, Kazuomi Tsuda, Toshiyuki Hamada, Hiroaki Okamura, Tatsuhiko Furukawa, Shin-ichi Akiyama, Yusuke Tajitsu, Ryuji Ikeda, Masaharu Komatsu, Matsumi Doe, Yoshiki Morimoto, Motoo Shiro, Rob W. M. van Soest, Kaoru Takemura, and Tetsuo Iwagawa
Journal of Natural Products2010 73 (9), 1512-1518
- Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata
  Miyabi Hirashima, Kazuomi Tsuda, Toshiyuki Hamada, Hiroaki Okamura, Tatsuhiko Furukawa, Shin-ichi Akiyama, Yusuke Tajitsu, Ryuji Ikeda, Masaharu Komatsu, Matsumi Doe, Yoshiki Morimoto, Motoo Shiro, Rob W. M. van Soest, Kaoru Takemura, and Tetsuo Iwagawa
  Journal of Natural Products2010 73 (9), 1512-1518
  Seven new isomalabaricane derivatives, rhabdastins A−G (1−7), and a new monocyclic triterpene glycoside, rhabdastoside A (8), have been isolated from the methanol extract of the sponge Rhabdastrella globostellata, collected at Amami-oshima, Japan. Three ...
  Abstract | Full Text HTML | Hi-Res PDF | PDF w/ Links