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Letter

In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

Supporting Info

Leonie Blackburn and Richard J. K. Taylor*

Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK

Org. Lett., 2001, 3 (11), pp 1637–1639

DOI: 10.1021/ol015819b

Publication Date (Web): May 5, 2001

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, rjkt1@york.ac.uk

Abstract

Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation−imine formation−reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

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History

Published In Issue May 31, 2001
Received March 9, 2001

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Letter

In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines