A CAN-Induced Cyclodimerization−Ritter Trapping Strategy for the One-Pot Synthesis of 1-Amino-4-aryltetralins from Styrenes

Vijay Nair,* Roshini Rajan, and Nigam P. Rath§
Organic Chemistry Division, Regional Research Laboratory (CSIR), Trivandrum, India, and Department of Chemistry, University of Missouri, St. Louis, Missouri 63121
Org. Lett., 2002, 4 (9), pp 1575–1577
DOI: 10.1021/ol0257934
Publication Date (Web): March 27, 2002
Copyright © 2002 American Chemical Society

 This paper is dedicated with respect and affection to Professor Gilbert Stork, a legend in his own time, for the gift of chemistry he has given to hundreds of students during the past six decades.

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*

 Fax:  +91-471-491712.

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 Regional Research Laboratory (CSIR).

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§

 University of Missouri.

, gvn@csrrltrd.ren.nic.in

Abstract

Abstract Image

A facile one-pot synthesis of 1-amino-4-aryl-tetralin derivatives by the CAN-induced cyclodimerization of various styrenes in acetonitrile and acrylonitrile is described.

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History

  • Published In Issue May 02, 2002
  • Received February 28, 2002

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