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Letter

Multifunctional Palladium Catalysis. 2. Tandem Haloallylation Followed by Wacker−Tsuji Oxidation or Sonogashira Cross-Coupling

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Avinash N. Thadani and Viresh H. Rawal*

Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637

Org. Lett., 2002, 4 (24), pp 4321–4323

DOI: 10.1021/ol0269603

Publication Date (Web): November 5, 2002

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, vrawal@uchicago.edu

Abstract

Multifunctional palladium catalysis is utilized in the one-pot stereocontrolled synthesis of tetrasubstituted methyl ketones and enynes. The homogeneous palladium dihalide catalyst utilized for the bromo-/chloroallylation of alkynes is reused in situ for subsequent Wacker−Tsuji oxidation or Sonogashira cross-coupling.

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Published In Issue November 28, 2002
Received September 25, 2002

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Letter

Multifunctional Palladium Catalysis. 2. Tandem Haloallylation Followed by Wacker−Tsuji Oxidation or Sonogashira Cross-Coupling

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Stereospecific Synthesis of Highly Substituted Skipped Dienes through Multifunctional Palladium Catalysis

Rhodium-Catalyzed 1,4-Additions to Enantiopure Acceptors: Asymmetric Synthesis of Functionalized Pyrrolizidinones

Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

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