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Letter

Direct Electrophilic Silylation of Terminal Alkynes

Supporting Info

Aleksey A. Andreev,*^† Valeri V. Konshin,^† Nikolai V. Komarov,^† Michael Rubin,^‡ Chad Brouwer,^‡ and Vladimir Gevorgyan*^‡

Kuban State University, 149 Stavropolskaya Street, Krasnodar, 350040 Russian Federation, and University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607

Org. Lett., 2004, 6 (3), pp 421–424

DOI: 10.1021/ol036328p

Publication Date (Web): January 15, 2004

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

†

Kuban State University.

‡

University of Illinois at Chicago.

, vlad@uic.edu

Abstract

A variety of alkynylsilanes were efficiently prepared via direct silylation of terminal alkynes with aminosilanes in the presence of zinc halides. Base- and nucleophile-sensitive functionalities were perfectly tolerated under the above reaction conditions. Initial mechanistic studies support the electrophilic character of this transformation.

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Published In Issue February 05, 2004
Received November 28, 2003

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Letter

Direct Electrophilic Silylation of Terminal Alkynes

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

Iridium-Catalyzed Addition of Acid Chlorides to Terminal Alkynes

Easily Attachable and Detachable ortho-Directing Agent for Arylboronic Acids in Ruthenium-Catalyzed Aromatic C−H Silylation

Copper-Catalyzed Aerobic Oxidative Coupling of Terminal Alkynes with H-Phosphonates Leading to Alkynylphosphonates

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