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Letter

Synthesis of Primary Amines by the Electrophilic Amination of Grignard Reagents with 1,3-Dioxolan-2-one O-Sulfonyloxime

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Mitsuru Kitamura, Takahiro Suga, Shunsuke Chiba, and Koichi Narasaka*

Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Org. Lett., 2004, 6 (24), pp 4619–4621

DOI: 10.1021/ol0479951

Publication Date (Web): October 27, 2004

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, narasaka@chem.s.u-tokyo.ac.jp

Abstract

Primary amines are prepared by the electrophilic amination of Grignard reagents with 4,4,5,5-tetramethyl-1,3-dioxolan-2-one O-phenylsulfonyloxime and the acidic hydrolysis of the resulting imines.

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Published In Issue November 25, 2004
Received October 1, 2004

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Letter

Synthesis of Primary Amines by the Electrophilic Amination of Grignard Reagents with 1,3-Dioxolan-2-one O-Sulfonyloxime