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Letter

Copper-Mediated Cross-Coupling Reactions of N-Unsubstituted Sulfoximines and Aryl Halides

Supporting Info

Gae Young Cho, Pauline Rémy, Jenny Jansson, Christian Moessner, and Carsten Bolm*

Institute of Organic Chemistry, RWTH Aachen University, Professor-Pirlet-Str. 1, D-52056 Aachen, Germany

Org. Lett., 2004, 6 (19), pp 3293–3296

DOI: 10.1021/ol048806h

Publication Date (Web): August 18, 2004

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, carsten.bolm@oc.rwth-aachen.de

Abstract

Copper-mediated cross-coupling reactions of sulfoximines with aryl iodides and aryl bromides provide N-arylated sulfoximines in high yields. The method is complementary to the known palladium-catalyzed N-arylation and allows the preparation of N-arylated sulfoximines, which have previously been inaccessible.

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History

Published In Issue September 16, 2004
Received June 23, 2004

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Letter

Copper-Mediated Cross-Coupling Reactions of N-Unsubstituted Sulfoximines and Aryl Halides