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Letter

Cu(OAc)₂-Catalyzed N-Arylations of Sulfoximines with Aryl Boronic Acids

Supporting Info

Christian Moessner and Carsten Bolm*

Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany

Org. Lett., 2005, 7 (13), pp 2667–2669

DOI: 10.1021/ol050816a

Publication Date (Web): May 20, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, carsten.bolm@oc.rwth-aachen.de

Abstract

A simple and mild copper salt-catalyzed N-arylation of sulfoximines in high yields is reported. Cu(OAc)₂ activates aryl boronic acids for the reaction with NH-sulfoximines without additional base or heating. Furthermore, this new method allows the preparation of N-arylated sulfoximines, which have previously been more difficult to access.

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History

Published In Issue June 23, 2005
Received April 14, 2005

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Letter

Cu(OAc)₂-Catalyzed N-Arylations of Sulfoximines with Aryl Boronic Acids