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Letter

Intramolecular Additions of Alcohols and Carboxylic Acids to Inert Olefins Catalyzed by Silver(I) Triflate

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Cai-Guang Yang, Nicholas W. Reich, Zhangjie Shi,^† and Chuan He*

Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637

Org. Lett., 2005, 7 (21), pp 4553–4556

DOI: 10.1021/ol051065f

Publication Date (Web): September 21, 2005

†

Current Address: Peking University, 202 Chengfu Road, Haidian District, Beijing 100871, P. R. China.

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, chuanhe@uchicago.edu

Abstract

Intramolecular additions of hydroxyl or carboxyl groups to inert olefins catalyzed by simple silver(I) triflate are described. Good to excellent yields can be obtained for a range of substrates under relatively mild conditions. This reaction represents one of the simplest methods to construct cyclic ethers or lactones.

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Published In Issue October 13, 2005
Received May 9, 2005
Revised September 2, 2005

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Letter

Intramolecular Additions of Alcohols and Carboxylic Acids to Inert Olefins Catalyzed by Silver(I) Triflate

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

Gold(I)-Catalyzed Intermolecular Addition of Phenols and Carboxylic Acids to Olefins

Platinum-Catalyzed Intramolecular Hydroalkoxylation of γ- and δ-Hydroxy Olefins to Form Cyclic Ethers

Indirect ortho Functionalization of Substituted Toluenes through ortho Olefination of N,N-Dimethylbenzylamines Tuned by the Acidity of Reaction Conditions

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