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Total Synthesis of Quinolizidine Alkaloid (−)-217A. Application of Iminoacetonitrile Cycloadditions in Organic Synthesis

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Kevin M. Maloney and Rick L. Danheiser*

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Org. Lett., 2005, 7 (14), pp 3115–3118

DOI: 10.1021/ol051185n

Publication Date (Web): June 15, 2005

Section:

Alkaloids

Abstract

An intramolecular iminoacetonitrile [4 + 2] cycloaddition functions as the key step in an efficient total synthesis of the quinolizidine alkaloid (−)-217A.

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Published In Issue July 07, 2005
Received May 19, 2005

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Letter

Total Synthesis of Quinolizidine Alkaloid (−)-217A. Application of Iminoacetonitrile Cycloadditions in Organic Synthesis

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

A Concise Total Synthesis of (±)-Minfiensine

A Stereocontrolled Synthesis of (+)-Saxitoxin

A Stereoselective Hydroamination Transform To Access Polysubstituted Indolizidines

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