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Letter

Highly Chemoselective Addition of Amines to Epoxides in Water

Supporting Info

Najmodin Azizi and Mohammad R. Saidi*

Department of Chemistry, Sharif University of Technology, P.O. Box 11465-9516, Tehran, Iran

Org. Lett., 2005, 7 (17), pp 3649–3651

DOI: 10.1021/ol051220q

Publication Date (Web): July 28, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, saidi@sharif.edu

Abstract

Aminolysis of a variety of epoxides by aliphatic and aromatic amines in water, in the absence of any catalyst with high yields, is reported. β-Amino alcohols were formed under mild conditions with high selectivity and in excellent yields.

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Published In Issue August 18, 2005
Received May 24, 2005

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Letter

Highly Chemoselective Addition of Amines to Epoxides in Water

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

Zinc(II) Perchlorate Hexahydrate Catalyzed Opening of Epoxide Ring by Amines: Applications to Synthesis of (RS)/(R)-Propranolols and (RS)/(R)/(S)-Naftopidils

Copper-Catalyzed Aerobic Oxidative Coupling of Terminal Alkynes with H-Phosphonates Leading to Alkynylphosphonates

Highly Efficient One-Pot Three-Component Mannich Reaction in Water Catalyzed by Heteropoly Acids

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