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Letter

Triarylborane Ammonia Complexes as Ideal Precursors for Arylzinc Reagents in Asymmetric Catalysis

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Stefan Dahmen* and Matthias Lormann

cynora GmbH, Kaiserstrasse 100, D-52134 Herzogenrath, Germany

Org. Lett., 2005, 7 (21), pp 4597–4600

DOI: 10.1021/ol0515659

Publication Date (Web): September 23, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, dahmen@cynora.de

Abstract

The value of arylboranes as precursors for arylzinc reagents in asymmetric catalysis is demonstrated. Kinetic studies on the transmetalation reaction with zinc reagents rationalize the observed differences of three classes of arylboranes in catalytic applications. By using the stable and easily accessible triarylborane ammonia complexes, an array of chiral diarylmethanols in high yield and enantioselectivity was synthesized.

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Published In Issue October 13, 2005
Received July 5, 2005

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Letter

Triarylborane Ammonia Complexes as Ideal Precursors for Arylzinc Reagents in Asymmetric Catalysis

Abstract

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History

Recommend & Share

Related Content

Highly Enantioselective Phenyl Transfer to Aryl Aldehydes Catalyzed by Easily Accessible Chiral Tertiary Aminonaphthol

Catalyzed Asymmetric Aryl Transfer Reactions to Aldehydes with Boronic Acids as Aryl Source

Highly Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides Catalyzed by Copper(I)/TF-BiphamPhos Complexes

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