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Letter

Cu(I)-Catalyzed Highly Exo-selective and Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides with Acrylates

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Wenzhong Gao, Xumu Zhang,* and Malati Raghunath

104 Chemistry Building, Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802

Org. Lett., 2005, 7 (19), pp 4241–4244

DOI: 10.1021/ol0516925

Publication Date (Web): August 13, 2005

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, xumu@chem.psu.edu

Abstract

A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.

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Published In Issue September 15, 2005
Received July 18, 2005

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Letter

Cu(I)-Catalyzed Highly Exo-selective and Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides with Acrylates

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

Highly Enantioselective Ag(I)-Catalyzed [3 + 2] Cycloaddition of Azomethine Ylides

Highly Enantioselective Copper(I)−Fesulphos-Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides

Catalytic Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides with Vinyl Sulfones

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