Triazole-Based Monophosphines for Suzuki−Miyaura Coupling and Amination Reactions of Aryl Chlorides

Duan Liu, Wenzhong Gao, Qian Dai, and Xumu Zhang*
Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802
Org. Lett., 2005, 7 (22), pp 4907–4910
DOI: 10.1021/ol051844w
Publication Date (Web): September 24, 2005
Copyright © 2005 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, xumu@chem.psu.edu

Abstract

Abstract Image

A new class of triazole-based monophosphine 1 (ClickPhos) has been prepared via efficient 1,3-dipolar cycloadditions of readily available azides and acetylenes. Palladium complexes derived from these ligands provide highly active catalysts for Suzuki−Miyaura coupling and amination reactions of aryl chlorides.

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History

  • Published In Issue October 27, 2005
  • Received August 2, 2005

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