An Iron-Containing Ionic Liquid as Recyclable Catalyst for Aryl Grignard Cross-Coupling of Alkyl Halides

Katharina Bica and Peter Gaertner*
Department of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, A-1060 Vienna, Austria
Org. Lett., 2006, 8 (4), pp 733–735
DOI: 10.1021/ol052965z
Publication Date (Web): January 26, 2006
Copyright © 2006 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, peter.gaertner@tuwien.ac.at

Abstract

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The ionic liquid butylmethylimidazolium tetrachloroferrate (bmim-FeCl4) was found to be a very effective and completely air stable catalyst for the biphasic Grignard cross-coupling with primary and secondary alkyl halides bearing β-hydrogens. After simply decanting the product in the ethereal layer, the ionic liquid catalyst was successfully recycled four times.

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History

  • Published In Issue February 16, 2006
  • Received December 7, 2005

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