Pd(0)-Catalyzed PMHS Reductions of Aromatic Acid Chlorides to Aldehydes

Kyoungsoo Lee and Robert E. Maleczka, Jr.*
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824
Org. Lett., 2006, 8 (9), pp 1887–1888
DOI: 10.1021/ol060463v
Publication Date (Web): April 7, 2006
Copyright © 2006 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, maleczka@chemistry.msu.edu

Abstract

Abstract Image

Contrary to previous reports, polymethylhydrosiloxane (PMHS) under Pd(0) catalysis can efficiently reduce aryl acid chlorides to their corresponding aldehydes without requiring an additional reductant, provided the reactions are run in the presence of fluoride.

View: Full Text HTML | Hi-Res PDF

Tools

History

  • Published In Issue April 27, 2006
  • Received February 22, 2006

Recommend & Share

Related Content

Other ACS content by these authors: