Norcysteine (Ncy) is an unnatural amino acid possessing an electronegative sulfur atom directly attached to the α-carbon atom. We describe the synthesis of Boc-d,l-Ncy(Mob)-OH, the resolution of its methyl ester, and the introduction of both d- and l-Ncy in GnRH analogues.
Citation data is made available by participants in CrossRef's Cited-by Linking
service. For a more comprehensive list of citations to this article, users are
encouraged to perform a search in SciFinder.
Samant, White, Hong, Croston, Conn, Janovick and Rivier
200750 (9), pp 2067–2077
Abstract: A series of acyline analogues incorporating l- and d-isomers of S-arylated/alkylated norcysteines [Ncy(R), where R is 2-naphthyl, methyl, and isopropyl] at positions 1, 4, 7, and 10 were synthesized. Some of these analogues were mono- and dioxidized to ...
Abstract: An enantioselective, catalytic aza-Sakurai cyclization of chlorolactams has been developed as an efficient entry into indolizidine and quinolizidine frameworks. Structure–enantioselectivity relationship studies and mechanistic analysis point to a dual ...
Abstract: We report the first total synthesis of the limonoid andirolide N using a 12-step sequence from commercially available materials. The final step of this route demonstrates the chemical feasibility of our biosynthetic proposal that andirolide N arises from ...
Learn more about these metrics
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.
The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.
