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Letter

Brønsted Acid Catalyzed Addition of Phenols, Carboxylic Acids, and Tosylamides to Simple Olefins

Supporting Info

Zigang Li, Junliang Zhang, Chad Brouwer, Cai-Guang Yang, Nicholas W. Reich, and Chuan He*

Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637

Org. Lett., 2006, 8 (19), pp 4175–4178

DOI: 10.1021/ol0610035

Publication Date (Web): August 18, 2006

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, chuanhe@uchicago.edu

Abstract

Intermolecular addition of phenols, carboxylic acids, and protected amines to inert olefins can be catalyzed by low concentrations (1−5%) of triflic acid. Functional groups, such as the methoxyl substitution on aromatics, could be tolerated if the concentration of triflic acid and the reaction temperature are controlled appropriately. This reaction provides one of the simplest olefin addition methods and is an alternative to metal-catalyzed reactions.

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Published In Issue September 14, 2006
Received April 26, 2006

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Letter

Brønsted Acid Catalyzed Addition of Phenols, Carboxylic Acids, and Tosylamides to Simple Olefins

Abstract

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SciFinder Links

History

Recommend & Share

Related Content

Hydroamination and Hydroalkoxylation Catalyzed by Triflic Acid. Parallels to Reactions Initiated with Metal Triflates

Gold(I)-Catalyzed Intra- and Intermolecular Hydroamination of Unactivated Olefins Gold(I)-Catalyzed Intra- and Intermolecular Hydroamination of Unactivated Olefins

Gold(I)-Catalyzed Intermolecular Addition of Phenols and Carboxylic Acids to Olefins

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