Letter
A Convenient Synthesis of 4-Alkyl-5-aminoisoxazoles
In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.
Abstract

A series of 4-alkyl-5-aminoisoxazoles have been synthesized in high yield by nucleophilic addition of lithiated alkyl nitriles to (α)-chlorooximes. The scope and limitations of this reaction were examined by varying the nature of the nitrile and chloride oxime.
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History
- Published In Issue August 17, 2006
- Received May 23, 2006
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