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Letter

Convenient Method for the Preparation of Weinreb Amides via Pd-Catalyzed Aminocarbonylation of Aryl Bromides at Atmospheric Pressure

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Joseph R. Martinelli, Dominique M. M. Freckmann, and Stephen L. Buchwald*

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Org. Lett., 2006, 8 (21), pp 4843–4846

DOI: 10.1021/ol061902t

Publication Date (Web): September 21, 2006

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, sbuchwal@mit.edu

Abstract

The direct transformation of aryl bromides into the corresponding Weinreb amides via Pd-catalyzed aminocarbonylation at atmospheric pressure is reported.

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Published In Issue October 12, 2006
Received August 1, 2006

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Letter

Convenient Method for the Preparation of Weinreb Amides via Pd-Catalyzed Aminocarbonylation of Aryl Bromides at Atmospheric Pressure

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Carbonylation of Aryl Chlorides with Oxygen Nucleophiles at Atmospheric Pressure. Preparation of Phenyl Esters as Acyl Transfer Agents and the Direct Preparation of Alkyl Esters and Carboxylic Acids

Palladium-Catalyzed Carbonylation of Aryl Tosylates and Mesylates

An Improved System for the Palladium-Catalyzed Borylation of Aryl Halides with Pinacol Borane

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